Its simply means that you have an array of values and you want record except that values/records.
you can simply pass a array into whereNotIn() laravel function.
With query builder
$users = DB::table('applications') ->whereNotIn('id', [1,3,5]) ->get(); //will return without applications which contain this id's
With eloquent.
$result = ModelClassName::select('your_column_name')->whereNotIn('your_column_name', ['satatus1', 'satatus2']); //return without application which contain this status.